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Postdoctoral Position in Signal Transduction and Transcriptional Regulation at UCLA
University of California Los Angeles
Postdoctoral Position in Signal Transduction and Transcriptional Regulation at UCLA
University of California Los Angeles
 University of California Los Angeles Requisition Number: JPF06768 Postdoctoral Position in Signal Transduction and Transcriptional Regulation at UCLA The laboratories of Dr. Elaine Reed (Immunogenetics Center, Department of Pathology and Laboratory Medicine) and Dr. Enrique Rozengurt (Signal Transduction Laboratory, Department of Medicine) in the David Geffen School of Medicine at UCLA are seeking applications for full-time Postdoctoral Positions. The focus of the projects will be to study the mechanisms of HLA class I and class II antibody-mediated graft injury leading to chronic antibody-mediated rejection (cAMR) with the aim of identifying potential therapeutic targets to prevent cAMR. These studies will include: 1) The role of the YAP/TAZ transcriptional program in promoting the proliferation and migration of endothelial cells (ECs) in response to HLA donor specific antibodies. 2) To investigate the mechanism(s) by which statins inhibit YAP function, proliferation and migration of ECs. 3) Characterize the impact of statins on YAP activity and cAMR in vivo using a novel model of heart graft allograft that develop transplant vasculopathy (TV). The candidate, a recent PhD, MD or DVM, must be enthusiastic, have strong written and oral communication skills, be highly motivated, intellectually creative, able to work independently, and function well as part of a team. Candidates will be expected to contribute to ongoing projects and expand novel independent research projects in a collaborative research environment. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy. Applying for the position Interested applicants should submit their CV as well as a cover letter indicating how their past research experience, interests, and goals connect to the activities of the laboratory. The letter should also include the names and contact information for three references. Please submit to: https://recruit.apo.ucla.edu/JPF06768. Deadline for applications: May 20, 2022 To apply, please visit: https://recruit.apo.ucla.edu/JPF06768 The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy, https://policy.ucop.edu/doc/4000376/DiscHarassAffirmAction jeid-7ef90d05ec606541af26c8893c42c424
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Internal Number: 2943465
UCLA is known worldwide for the breadth and quality of its academic, research, health care, cultural, continuing education and athletic programs. UCLA offers undergraduate degrees in more than 127 majors and graduate degrees in 198 program areas. UCLA has 11 highly regarded professional schools. Eight are ranked among the nation's top 15 in their field by U.S. News & World Report. UCLA is consistently among the most popular campus in the nation for undergraduate applicants. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, national origin, disability, or protected veteran status. Benefits:UCLA offers a comprehensive benefits package, including an average of three weeks' vacation per year; an average of 12 days per year sick leave; 13 paid holidays per year; health, dental and optical benefits; life insurance; disability insurance; the University of California Retirement Plan with 5 year vesting and various voluntary UC Savings Plans. There are also special programs and privileges available, such as accessibility to cultural and recreational programs, athletic events, and the University Credit Union.
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